Selective loss of slow and enhancement of fast Na+currents in cutaneous afferent dorsal root ganglion neurones following axotomy
Voltage-dependent Na+currents were recorded via patch-clamp from identified adult rat lumbar cutaneous dorsal root ganglion (DRG) neurones using Computer PS2 Cable whole-cell and bleb-patch-clamp configurations.Na+currents in DRG neurones studied 18 days after sciatic nerve ligation were compared with those in control neurones.Control neurones tend